Predict The Future?



There are few studies that offer us some insight on what this disease will do in the long run.  I was able to find one such article though and it was eye opening for me.  I want to share some of the key points with you.


  • Spondy’s have a 50% increased risk of mortality compared to the general population.
  • While the disease is strongest in the first ten years it is clear it remains active and some of the studies showed it was hard to determine a difference between the first decade and following..
  • The burden of disease is longer in those with AS opposed to RA.
  • Absence from work and disability is greatly increased compared to general population.
  • What affects a Spondy’s quality of life?  This study found 90% was stiffness, 83% pain, 62% fatigue, and 54% disruption of sleep.
  • After 16 years of disease activity only 50% of Spondy’s were still employed.
  • Men and woman faired equally on daily burdens.
  • Frequent fractures resulting from minimal trauma was common.
  • Low Bone Density


Some predictors of more severe disease activity;

  • Co-exist with other auto-immune disorders.
  • Early limitation of spine.
  • Peripheral Involvement
  • Dactylitis
  • Iritis
  • Kidney/Liver Involvement
  • Cervical and lumbar involvement was noted with longer disease activity.
  • Amyloidosis
  • Hypergammaglobulinemia


Stats on cause of death;











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