There are few studies that offer us some insight on what this disease will do in the long run. I was able to find one such article though and it was eye opening for me. I want to share some of the key points with you.
- Spondy’s have a 50% increased risk of mortality compared to the general population.
- While the disease is strongest in the first ten years it is clear it remains active and some of the studies showed it was hard to determine a difference between the first decade and following..
- The burden of disease is longer in those with AS opposed to RA.
- Absence from work and disability is greatly increased compared to general population.
- What affects a Spondy’s quality of life? This study found 90% was stiffness, 83% pain, 62% fatigue, and 54% disruption of sleep.
- After 16 years of disease activity only 50% of Spondy’s were still employed.
- Men and woman faired equally on daily burdens.
- Frequent fractures resulting from minimal trauma was common.
- Low Bone Density
Some predictors of more severe disease activity;
- Co-exist with other auto-immune disorders.
- Early limitation of spine.
- Peripheral Involvement
- Kidney/Liver Involvement
- Cervical and lumbar involvement was noted with longer disease activity.
Stats on cause of death;
- Cardiovascular was the leading cause at 35%.
- 29% Ankylosing Spondylitis listed as cause.
- 10% Violent
- 6% gastrointestinal
- 3% Pulmonary Tuberculosis
- 3% Urogenital Disease
- 4% Respiratory Disease
- 1% Diabetes